THE TIDE MODEL OF T CELL COSTIMULATION »
Lafferty and Cunningham postulated in 1975 that T cells require two signals for proper activation. T cell receptor binding to a MHC-peptide complex on the surface of an antigen presenting…
Sep 11 2011 / 1 Comment / Read More »Fast CARs for cancer treatment »
Cancer immunotherapy is a hot topic. In the last year we have seen the approval of two different cancer treatments…
Sep 19 2011 / No Comment / Read More »MECHANISMS OF IMMUNE ESCAPE BY TUMORS »
Hanahan and Weinberg did not take into account the concept of immune escape as a “hallmark of cancer” ten years…
Sep 11 2011 / 1 Comment / Read More »WHAT IS CANCER IMMUNOSURVEILLANCE? »
Ehrlich postulated the link between the immune system and the control of tumors more than 100 years ago. Burnet and…
Sep 2 2011 / No Comment / Read More »










